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EXPLANATION
✔Correct answer:
Digoxin (Lanoxin). Digoxin is often prescribed to infants with Tetralogy of Fallot (TOF) to improve cardiac function. Tetralogy of Fallot is a congenital heart defect characterized by four structural abnormalities: pulmonary stenosis, ventricular septal defect (VSD), overriding aorta, and right ventricular hypertrophy. These defects can lead to poor oxygenation, cyanosis, and decreased cardiac output. Digoxin works by improving myocardial contractility (positive inotropic effect), which strengthens the heart’s pumping ability and enhances blood flow. Additionally, it has a negative chronotropic effect (slows the heart rate), allowing the ventricles more time to fill and pump blood effectively.
Although Digoxin does not correct the structural abnormalities, it can stabilize cardiac function and help manage symptoms such as fatigue, poor feeding, and low oxygenation. This is especially important as surgical correction of TOF is usually performed later, allowing the infant to grow stronger before undergoing repair.
In TOF, improved cardiac output helps minimize the frequency and severity of "Tet spells" (hypercyanotic episodes caused by decreased pulmonary blood flow), reduces strain on the heart, and supports overall growth and development.
Imagine the heart as a weak water pump trying to push water (blood) through a clogged system (structural defects in TOF). Digoxin strengthens the pump’s force and helps it deliver water (blood) more effectively, even with some obstructions.
When administering Digoxin to Baby Liam, the nurse must ensure safe and effective use by closely monitoring the following:
- Apical heart rate: Measure the infant's apical pulse for 1 full minute before administration. Withhold the medication and notify the healthcare provider if the heart rate is below the prescribed threshold (typically <90–110 beats per minute in infants).
- Signs of Digoxin toxicity: Watch for symptoms such as vomiting, bradycardia, poor feeding, lethargy, or arrhythmias, which could indicate toxicity.
- Serum Digoxin levels: Monitor therapeutic levels (0.8–2.0 ng/mL for infants) to avoid toxicity. Therapeutic drug monitoring is especially important due to the narrow therapeutic range.
- Electrolyte levels: Ensure potassium levels are within the normal range, as hypokalemia increases the risk of Digoxin toxicity.
- Parental education: Teach parents how to administer Digoxin safely at home, including the importance of correct dosing, signs of toxicity, and the need for regular follow-up appointments.
✘Incorrect answer options:
Epinephrine (Adrenalin): Epinephrine is not used for long-term management of Tetralogy of Fallot. It is reserved for emergency situations, such as cardiac arrest or anaphylaxis, where immediate stimulation of the heart is needed. Its effects—raising heart rate and blood pressure—are not appropriate for routine care of TOF, as they can worsen the heart's workload.
Aminophylline: Aminophylline is a bronchodilator used in respiratory conditions such as asthma or bronchospasm. It has no role in managing Tetralogy of Fallot, as it does not address cardiac function or structural heart defects.
Atropine: Atropine is typically used in emergency situations for bradycardia or to reduce secretions during procedures. It does not improve myocardial contractility or blood flow and is not relevant to the management of TOF.
References
- Hinkle, J. L., & Cheever, K. H. (2018). Brunner & Suddarth's Textbook of Medical-Surgical Nursing. Wolters Kluwer.
- McKinney, E. S., James, S. R., Murray, S. S., Nelson, K. A., & Ashwill, J. W. (2017). Maternal-Child Nursing. Elsevier.