9. Nurse Carla is caring for a 51-year-old widower admitted with diabetes mellitus, rapid-onset weight loss, high blood glucose levels, and polyphagia. Given these symptoms, what secondary medical diagnosis should the nurse anticipate?
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EXPLANATION
✔Correct answer:
Pancreatic tumor. Given the patient's symptoms of diabetes mellitus, rapid-onset weight loss, high blood glucose levels, and polyphagia, Nurse Carla should anticipate a secondary medical diagnosis of a pancreatic tumor, specifically pancreatic cancer. Pancreatic tumors, particularly in the pancreas' endocrine part (like insulinomas or other neuroendocrine tumors), can impact insulin production and lead to significant metabolic disturbances.
Pancreatic cancer is known for its poor prognosis and rapid progression, and it often presents with nonspecific symptoms like weight loss, new-onset diabetes, and abdominal pain. Diabetes mellitus, especially when it develops rapidly and is associated with other systemic symptoms like weight loss and polyphagia, can be an early sign of pancreatic cancer. The tumor may cause either an overproduction of insulin or impede the production of insulin, leading to uncontrolled blood glucose levels and the symptoms described.
The pancreas plays a crucial role in regulating blood glucose levels through the secretion of insulin. A tumor in the pancreas can disrupt this process, leading to insulin deficiency or resistance, which manifests as hyperglycemia (high blood glucose levels). The rapid weight loss occurs because the body, unable to use glucose for energy, starts breaking down fat and muscle for fuel. Polyphagia (increased appetite) occurs as the body attempts to compensate for the energy deficit despite high blood glucose levels.
Think of the pancreas as a factory that produces insulin, a key that helps sugar enter cells to be used for energy. If the factory has a malfunction (like a tumor), it might not produce enough keys, leading to sugar accumulating in the blood, which can cause the symptoms seen in diabetes and rapid weight loss.
Nurse Carla should be prepared for potential diagnostic tests like imaging (e.g., CT scan or MRI) to confirm the presence of a pancreatic tumor. She should also monitor the patient's blood glucose levels closely and be alert for signs of complications such as diabetic ketoacidosis.
- Educate the patient on the importance of diagnostic testing to determine the underlying cause of his symptoms.
- Monitor blood glucose levels regularly and administer insulin as prescribed to manage hyperglycemia.
- Provide nutritional support to address the rapid weight loss and ensure the patient maintains adequate nutritional intake.
- Be attentive to the patient's emotional needs, as a diagnosis of pancreatic cancer can be particularly distressing.
✘Incorrect answer options:
Impaired glucose tolerance. Impaired glucose tolerance (IGT) is a prediabetic state of hyperglycemia that is associated with insulin resistance and is not typically linked with rapid-onset symptoms like weight loss and severe hyperglycemia. IGT does not explain the acute symptoms of weight loss and polyphagia that suggest a more severe underlying condition.
Gestational diabetes mellitus. Gestational diabetes mellitus (GDM) occurs during pregnancy and is therefore not relevant to a 51-year-old male patient. It is a condition where glucose intolerance is first recognized during pregnancy and would not be considered in this case.
Pituitary tumor. While a pituitary tumor can affect multiple hormonal pathways and potentially lead to symptoms like weight loss, it is not directly associated with diabetes mellitus, especially the type presenting with rapid-onset symptoms like in this case. The focus should remain on the pancreas given the specific symptoms.
References
- American Diabetes Association. (2023). Standards of Medical Care in Diabetes—2023. Diabetes Care, 46(Supplement_1), S1-S291.
- Vincent, A., Herman, J., Schulick, R., Hruban, R. H., & Goggins, M. (2011). Pancreatic cancer. The Lancet, 378(9791), 607-620.